Definitely. There's around 5-6k who haven't renewed and they've had very little uptake from new ST holders so there's far more seats to fill on a match by match basis at hugely inflated prices.
As a comparison I'm pretty sure Spurs at home last season didn't make general sale (if it did it was literally just a handful of tickets) and this season there's going to be 1000s available. Might not even sell out. Speaking personally I haven't renewed my ticket and I have no intention of paying £40+ which will be the general sale price, to watch individual matches, and I think the majority will have a similar mindset.